By M.D. Esben Kirk
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Extra info for Acidosis. Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate Solution
Since acidosis, as stated on p. ), which manifests itself in a reduction of the plasma chloride value, the administration of physiological sodium chloride solution is often indicated. The amount of saline to be administered depends on the degree of loss; as a rule 1 or 2 litres a day will be sufficient, but in severe cases of dehydration (e. g. in cholera) the doses (even with simultaneous administration of isotonic bicarbonate solution) must often be increased to 5-10 litres. The treatment should be continued until the chloride value of the plasma has become normal.
During the injection of the concentrated alkaline solution consciousness gradually returned, by degrees the respiration grew calmer, and the patients began to talk. Almost regularly an improvement of 12-14 hours' duration set in, which in many apparently hopeless cases was the beginning of the patients' recovery. Often, however, it was necessary after the lapse of 24 hours to give one more sodium carbonate injection. According to the estimate of Elias the treatment was life-saving in one-fourth of the cases.
In the evening (2 litres). Thus in the course of 14 hours, 7 injections comprising in all 15 litres of fluid had been given. 100, and the general condition so good that further treatment with injections was considered unnecessary. Apart from pronounced fatigue the recovery now proceeded rapidly. Dr. Weatherhill concludes his report with these words: »It will readily be perceived t h a t m u c h time and attention w e r e given to this case. Had t h e r e been less, it must have terminated in another way.
Acidosis. Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate Solution by M.D. Esben Kirk