By Karen S. Canady (auth.), Shirley Pease, Thomas L. Saunders (eds.)
This laboratory guide, released in cooperation with the foreign Society for Transgenic know-how (ISTT), offers just about all present equipment that may be utilized to the construction and research of genetically converted animals. The chapters were contributed by way of prime scientists who're actively utilizing the expertise of their laboratories. in response to their first-hand adventure the authors additionally offer invaluable notes and troubleshooting sections.
Topics variety from usual ideas, equivalent to pronuclear microinjection of DNA, to extra refined and smooth tools, similar to the derivation and institution of embryonic stem (ES) cellphone strains, with outlined inhibitors in telephone tradition medium. furthermore, comparable subject matters with relevance to the sphere are addressed, together with international web-based assets, felony concerns, colony administration, cargo of mice and embryos, and the 3 R’s: refinement, aid and replacement.
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Extra info for Advanced Protocols for Animal Transgenesis: An ISTT Manual
The additional element added in dependent claim 14, further comprising isolating the heterologous peptide from the transgenic avian or an egg laid by the transgenic avian, contemplates an obvious step that would be employed in commercial applications of the invention. This adds an additional claim that would likely be infringed by an entity found to be infringing any of the other claims. The Rapp patent contains an additional series of claims that include a slightly different independent claim and a parallel set of dependent claims.
This patent to Deboer et al. indicates also that it is based on a divisional application from “application Ser. No. 08/154,019 filed Nov. S. Pat. No. S. patent application Ser. No. 08/077,788, filed Jun. S. patent application Ser. No. 07/898,956, filed Jun. S. patent application Ser. No. 07/ 619,131 filed Nov. S. patent application Ser. No. 07/444,745 filed Dec. 1, 1989 now abandoned. ” This latter sentence is a safeguard against having failed to include 22 Canady material from any of the prior related applications.
One can hire a professional search service to assist in identifying patents that may block a particular area of endeavor, or search the patent database oneself. The identification of relevant patents is but a starting point in the analysis of freedom to operate. One must then review the claims and the related file history. Retaining the services of a qualified professional is strongly recommended prior to the investment of significant sums in practicing a technology. If the desired activity is blocked by one or more patent holders, one can explore the feasibility of working around the patent claims, seeking appropriate licenses, or entering into a joint development agreement.
Advanced Protocols for Animal Transgenesis: An ISTT Manual by Karen S. Canady (auth.), Shirley Pease, Thomas L. Saunders (eds.)